منابع مشابه
Pinning down NuMA
and colleagues have found that cells need a particular transcription factor to survive in the hypoxic interior of developing bones. The critical activity of hypoxia-inducible factor 1 ␣ (HIF-1 ␣), they say, is probably its induction of a glycolytic metabolism appropriate to a R HIF-1␣ prevents cell death despite hypoxia (red) in a wild-type tibia. low oxygen environment. Without this metabolic ...
متن کاملPinning Down Randomness
While some behavioral responses to a stimulus are invariant in animals, most are more likely to be variable or stochastic. In this issue, Gordus et al. illuminate a set of combinatorial neuronal activities that control the variability of a chemotactic behavior in response to an odor, providing a tractable system for understanding how stochastic circuit dynamics affect behavior.
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We analyse high-resolution archival UVES data of turnoff and subgiant stars in the nearby globular cluster NGC6397 ([Fe/H]≈−2). Balmer-profile analyses are performed to derive reddening-free effective temperatures. Due to the limited S/N and uncertainties related to blaze removal, we find the data quality insufficient to exclude the existence of gravitational settling. If the newly derived effe...
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There is a wide variety of work being done by artists working both in conventional genres such as Music, Dance and Theatre as well as newly emergent hybrid and innovative forms such as real-time animation and physically distributed and telematic performance. I want to build up a picture both of what technical resources artists are employing – and to what effect technology is being used; what th...
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According to leading investigators in the field of cellular signal transduction, the epidermal growth factor (EGF) receptor (EGFR, ErbB1, HER1), ubiquitously encountered in signaling mechanisms and thus in human tumors, is the best studied yet least prototypic of receptor tyrosine kinases in general (1). This perception arises primarily from the fact that activation of the EGFR is thought to be...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2004
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm1455